Diabetic neuropathy

EBM Guidelines
Jun 16, 2023 • Completely updated
Esa Mervaala and Milla Rosengård-Bärlund

Table of contents

Extract

  • The diagnosis of diabetic neuropathy is based on the diagnosis of diabetes, typical symptoms and clinical findings, as well as exclusion of other causes leading to neuropathy.
  • Neuropathy that affects the large fibres can be verified objectively by ENMG Clinical neurophysiology in diagnostics1 and small fibre neuropathy by quantitative sensory threshold testing or skin biopsy.
  • Diabetic neuropathy may be the first sign of type 2 diabetes or impaired glucose tolerance.
  • Up to 50% of cases of diabetic neuropathy are asymptomatic.
  • The loss of protective sensation as a consequence of peripheral neuropathy is the most important risk factor of diabetic foot ulcer.
  • Diabetic neuropathy increases morbidity and mortality.
  • It is important to identify neuropathy early and possibly prevent developing neuropathy.

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Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetes mellitus, Diabetic Neuropathies, E10.4, E10.6, E11.4, E11.6, Endocrinology, Femoral Neuropathy, G59*, G63.2*, G99.0*, Gastroparesis, Heart Rate, Hypotension, Orthostatic, Internal medicine, Methotrimeprazine, Mononeuropathies, Neurology, Ophthalmoplegia, Radiculopathy, Reflex, Stretch, Somatosensory Disorders, asymmetric polyneuropathy, autonomic neuropathy, blood pressure, systolic, diabetic amyotrophy, multiple mononeuropathy, neuropathic pain, neuropathy, ocular nerve, proximal neuropathy, resting heart rate, thoracic spine radiculopathy