Myelodysplastic syndromes (MDS)

Extract

• Myelodysplastic syndromes (MDS) are malignant blood diseases characterized by decreased haematological values and a tendency to develop into acute leukaemia.
• MDS should be suspected particularly in an elderly patient with unexplained macrocytic anaemia, which may be associated with leucopenia or thrombocytopenia.
• Cytopenias in the blood count result from inefficient bone marrow function caused by dysplasia i.e. a disorder of differentiation and maturation of myeloid cell lines.

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Bone Marrow Examination, D46*, Erythrocyte Transfusion, Haematology, Hemoglobins, Internal medicine, Myelodysplastic Syndromes, allogeneic stem-cell transplantation, ringed sideroblast