Guillain-Barré syndrome (polyradiculitis)
EBM Guidelines
Feb 15, 2022 • Latest change Feb 15, 2022
Table of contents
Extract
- Guillain–Barré syndrome (polyradiculitis, polyneuritis) denotes an inflammation of unknown origin of nerve roots that affects mainly the motor nerves and has an ascending course.
- Remember the possibility of polyneuritis (polyradiculitis) in a patient presenting with limb weakness or numbness.
- The patient is treated in a hospital where mechanical ventilator treatment is available.
- See also the Orphanet article ORPHA2103 https://www.orpha.net/consor/cgi-bin/Disease_Search.php?lng=EN&data_id=8341.
Read full article of Guillain-Barré syndrome (polyradiculitis)
Linked evidence summaries
- Corticosteroids appears not to hasten recovery from Guillain-Barré syndrome or affect the long-term outcome. Oral corticosteroids appear to delay recovery.B
- Intravenous immunoglobulin started within two weeks from the onset of severe Guillain-Barre syndrome hastens recovery as much as plasma exchange.A
- Plasma exchange is beneficial in Guillain-Barré syndrome: after one year, full recovery is more likely and severe residual weakness less likely than with supportive care.A
Search terms
Cerebrospinal Fluid, Cerebrospinal Fluid Proteins, Electromyography, G61.0, Guillain-Barre Syndrome, Neurology, Paralysis, Polyradiculopathy, Radiculopathy, polyradiculitis