Drugs used in alcohol dependence
EBM Guidelines
Feb 8, 2021 • Latest change Sep 6, 2021
Table of contents
Extract
- Alcohol dependence is a chronic illness the prognosis of which may be improved with drug therapy.
- Psychosocial therapies without combination with drug therapy provide moderate effect in mild or moderate alcohol dependence. Continuity of care and good therapeutic relationship are essential.
- Supervised medication with naltrexone ?, disulfiram ? or acamprosate ?, when combined with psychosocial therapies will improve therapy outcomes.
- Counselling that supports reduction of alcohol consumption and that is combined with nalmefene medication ? reduces alcohol intake in persons with mild to moderate alcohol dependence.
- The best results have been achieved by combining pharmacological agents with therapy aimed at controlling alcohol use and preventing relapses and with family and network therapies. Treatment methods applying the cognitive framework have been proven effective.
- The possibility to provide therapy with naltrexone, disulfiram and acamprosate should be available in all healthcare services. Other medications or medication combinations are best suited for use primarily in units specializing in the care of alcohol and drug abusers.
Linked evidence summaries
Search terms
Acamprosate, Addiction, Alcohol, Alcohol Deterrents, Alcohol Drinking, Alcohol abstinence, Alcohol addiction, Alcohol dependence, Alcohol withdrawal, Alcohol-related diseases, Alcoholism, Disulfiram, F10.2*, Naltrexone, Z72.2