Infective endocarditis

EBM Guidelines
Oct 5, 2022 • Latest change Sep 7, 2023
Janne Laine and Essi Ryödi

Table of contents

Extract

  • The prompt diagnosis of infective endocarditis is important as the condition is treatable but will almost always prove fatal if left untreated.
  • Diagnostics, treatment and partly also follow-up takes place within specialized care in collaboration with different specialties (cardiologist, throracic surgeon, infectious disease physician and, if needed, other specialists, such as a psychiatrist).
  • Factors predisposing to endocarditis are
    • a history of severe valvular disease
    • prosthetic heart valve
    • congenital heart disease (e.g. aortic stenosis, bicuspid aortic valve, septal defect, coarctation of the aorta)
    • a history of endocarditis
    • foreign body in the cardiovascular system
    • haemodialysis
    • immunosuppression
    • bad condition of the teeth
    • use of intravenous illegal drugs.
  • Should be suspected especially in febrile patients with a factor predisposing to endocarditis, bacteraemia and
    • a new heart murmur on auscultation or
    • clinical signs matching those seen in septic emboli (e.g. in the brain, lungs or skin)
    • the infection focus is unclear.
  • Diagnosis is based on the clinical picture, a positive blood culture result (in 80–90% of patients with endocarditis) and echocardiography.
  • In order to rule out endocarditis, echocardiography is indicated for most patients with sepsis caused by Staphylococcus aureus or candida.

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Bacterial endocarditis, Cardiology, Endocarditis, Endocarditis, Bacterial, Endocarditis, Subacute Bacterial, I33, I33.0, I33.9, I38, I39.8*, Infectious diseases, Infectious endocarditis, Infective endocarditis, Internal medicine, Prophylaxis, prosthetic endocarditis