Infective endocarditis
EBM Guidelines
Oct 5, 2022 • Latest change Sep 7, 2023
Table of contents
Extract
- The prompt diagnosis of infective endocarditis is important as the condition is treatable but will almost always prove fatal if left untreated.
- Diagnostics, treatment and partly also follow-up takes place within specialized care in collaboration with different specialties (cardiologist, throracic surgeon, infectious disease physician and, if needed, other specialists, such as a psychiatrist).
- Factors predisposing to endocarditis are
- a history of severe valvular disease
- prosthetic heart valve
- congenital heart disease (e.g. aortic stenosis, bicuspid aortic valve, septal defect, coarctation of the aorta)
- a history of endocarditis
- foreign body in the cardiovascular system
- haemodialysis
- immunosuppression
- bad condition of the teeth
- use of intravenous illegal drugs.
- Should be suspected especially in febrile patients with a factor predisposing to endocarditis, bacteraemia and
- a new heart murmur on auscultation or
- clinical signs matching those seen in septic emboli (e.g. in the brain, lungs or skin)
- the infection focus is unclear.
- Diagnosis is based on the clinical picture, a positive blood culture result (in 80–90% of patients with endocarditis) and echocardiography.
- In order to rule out endocarditis, echocardiography is indicated for most patients with sepsis caused by Staphylococcus aureus or candida.
Search terms
Bacterial endocarditis, Cardiology, Endocarditis, Endocarditis, Bacterial, Endocarditis, Subacute Bacterial, I33, I33.0, I33.9, I38, I39.8*, Infectious diseases, Infectious endocarditis, Infective endocarditis, Internal medicine, Prophylaxis, prosthetic endocarditis